Method Development for Simultaneous Estimation of Antiviral Drugs Sofosbuvir and Ledipasvir

Abstract

The pharmaceutical industry is currently developing novel antiviral medications, available in either single or co-formulated tablet form. Economic and therapeutic policies are stimulating interest in the burgeoning market for antiviral medications. Consequently, there is an urgent need to validate analytical processes that monitor all parameters regarding quality, safety, and efficacy with optimal efficiency and precision while minimizing costs. High-performance liquid chromatography (HPLC) and ultraviolet (UV) spectroscopy provide an automated, rapid, and highly accurate method for detecting particular chemical constituents in a sample. This approach is used in many labs for chemical measurement and separation, including those focused on medicine, forensics, bioavailability, environmental studies, and industrial applications. Sofosbuvir, ledipasvir were antiviral medications that were quantitatively studied using HPLC methodology.