Spectrum of Non-Neoplastic Lesions of the Large Intestine- A Two-Year Study at a Tertiary Care Centre.

Abstract

Background:

It is challenging to diagnose intestinal lesions using clinical examination and radiographic examinations due to the great morphologic variety. The goal of our research is to thoroughly examine and analyze the many non-neoplastic lesions of the large intestine using histopathology.

Materials and methods:

It's a retrospective study, conducted for 2-years duration (May 2022- May 2024). It was conducted at MGM Medical College, Chhatrapati Sambhaji Nagar (Aurangabad). A total of 557 samples were examined in the study. Histopathologic findings, clinical features, and colonoscopic findings were analysed.

Results:

A total of 557 patients were recruited for the study. Among these, 47.4% were males and 52.6% were females. Site-wise distribution showed maximum number of cases involved the appendix, followed by the colon and rectum. On further evaluation with colonoscopy, the gross features showed majority with apthous ulcers and wall thickening. In our study, abdominal pain was the most common presenting complaint, followed by loose stools and bleeding per rectum. The histopathological evaluation showed that majority had recurrent appendicitis and acute appendicitis.

Conclusion:

In summary, intestinal lesions exhibit morphological variety while also exhibiting a notable commonality in clinical presentations. The significance of histological analysis in the treatment of colonic lesions is emphasized by our work.