From Bench to Bedside: Advances in the Synthesis of Dibenzosuberane Derivatives and Enhanced Bioactivity
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Dibenzosuberane and dibenzosuberenone scaffolds are widely recognized as important structural frameworks in modern medicinal chemistry and in the synthesis of diverse organic compounds. This review summarizes recent synthetic strategies used to prepare dibenzosuberane and dibenzosuberenone derivatives and discusses their significant biological activities, including potent antidepressant, anticonvulsant, antiproliferative and other pharmacological properties. This study provides a precise overview of suberane and suberenone pharmaceuticals and their wider industrial applications.
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