Formulation and Evaluation of Calendula Officinalis and Melaleuca Alternifolia- based Poly-Herbal Paper Soap for Enhanced Antimicrobial and Antioxidant Efficacy.

Abstract

Background: Herbal hygiene products have become incredibly popular in a time when people are gravitating toward natural and sustainable options. This study investigates the possibility for developing novel personal care products using two well-known medicinal plants: Melaleuca alternifolia (tea tree oil) and Calendula officinalis (pot marigold). While tea tree oil has potent antibacterial and antifungal properties, calendula officinalis is renowned for its wound-healing, anti-inflammatory, and antioxidant properties. The goal of the study was to create and evaluate product that combine both herbal agents for better skincare and hygiene: polyherbal paper soap.

Methodology: Three formulations (F1, F2, and F3) with different ratios of herbal oils and excipients were created in the form of paper soap. The liquid soap coating process was used to make the paper soap. Agar diffusion was used to assess its pH, moisture content, skin irritation, foam retention, antioxidant activity, and antibacterial properties against S. aureus and E. coli.

Results and Discussion: F3 was the most successful formulation out of all of them. It had the most antioxidant capacity and the strongest antibacterial action, especially against S. aureus. The product's effectiveness was greatly enhanced by the addition of calendula and tea tree oil, which worked in concert to provide antibacterial and skin-soothing effects.

Conclusion: Three forms of a safe, all-natural, and efficient herbal hygiene product were effectively developed by the study.