Clinical Profile of Infertile PCOS Women Attending in BSMMU
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Abstract
Background: Polycystic ovary syndrome (PCOS) is a leading endocrine disorder and major cause of female infertility, characterized by heterogeneous clinical presentations. Understanding the specific profiles of infertile women with PCOS in different populations is crucial for timely diagnosis and effective management. This study aimed to evaluate the clinical and hormonal profiles of infertile women diagnosed with PCOS who attended the infertility clinic at Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh.
Methods: This cross-sectional observational study was conducted at the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh, from January 2007 to December 2007. A total of 100 women with PCOS and infertility were included. Data were collected through interviews, physical examinations, hormonal assays (LH, FSH, and testosterone), and transvaginal sonography. Descriptive and inferential statistical analyses were conducted using SPSS version 25.0, with a significance level set at p≤0.05.
Results: Secondary infertility was more prevalent (72%) than primary infertility (36%) in this study. Oligomenorrhea was observed in 60% of the participants, and 44% exhibited hirsutism. Obesity was present in 42% of patients, while 46% had a normal body mass index (BMI). An LH: FSH ratio >1:3 was found in 56% of patients, and elevated serum testosterone levels were observed in 30% of patients. Polycystic ovarian morphology on transvaginal sonography was detected in 52% of the patients.
Conclusion: Infertile women with PCOS at BSMMU exhibit a broad spectrum of clinical and hormonal features, with oligomenorrhea, obesity, and hyperandrogenism being dominant. These findings highlight the need for individualized and culturally tailored management strategies.