Association between Index of Central Obesity and Lipid Profile in Obese Type 2 Diabetes

Abstract

Background: The Index of central obesity (ICO) is defined as a ratio of waist circumference and height and is a better parameter of central obesity. To quantify proportion of visceral fat in the total body fat, waist circumference alone is not sufficient.

Objective: To observe the relation between ICO and lipid profile in obese type 2 diabetes mellitus.

Materials and Methods: The present study was carried out at rural based clinic located near to Apollo Medical College region, Chittoor, Andhra Pradesh, after a written consent from all the participants. The study includes 515 diabetic patients, in which 356 were males and159 were females. The Index of central obesity were measured by taking the waist circumference and height and about 5 ml of blood  was collected and used for the estimation of serum cholesterol, triglyceride and HDL-Cholesterol levels by using standard methods. Statistical analysis was done by using independent student t test and Pearson Correlation coefficient was calculated.

Results: The ICO and lipid profiles were not significantly correlated. In type 2 diabetes male patients showed higher triglycerides (177.96±100.19) with waist hip ratio>0.9, whereas female patients showed less Triglycerides (178.19±99.52) with waist hip ratio >0.8. However these differences were statistically not significant.

Conclusion: Multiple anthropometric parameters are required to correlate lipid profile rather than single parameter in type 2 diabetes mellitus. Along with anthropometric measurements, lipid profile is also need to be monitored in type 2 diabetics.