Functional and Oncological Outcomes of Modular Endoprosthetic Reconstruction in Bone Sarcomas: A Two-Year Follow-Up Study

Abstract

Background: Bone sarcomas present unique challenges in orthopaedic oncology due to their aggressive nature and high recurrence rates. Modular endoprosthetic reconstruction has emerged as a preferred limb-salvage technique, offering functional restoration and oncological safety.

Objective: This study aimed to evaluate the functional and oncological outcomes of modular endoprosthetic reconstruction in patients with bone sarcomas over a two-year follow-up period.

Methods: A retrospective observational study was conducted on 38 patients diagnosed with bone sarcomas who underwent modular endoprosthetic reconstruction. Functional outcomes were assessed using the Musculoskeletal Tumour Society (MSTS) scoring system, while oncological outcomes included recurrence, metastasis, and survival rates. Data on complications, including infections and prosthetic failure, were also analysed.

Results: The mean MSTS score was 24.8, indicating good functional recovery. Local recurrence occurred in 10.5% of cases, and distant metastases in 15.8%. The two-year disease-free and overall survival rates were 73.7% and 84.2%, respectively. Complications were observed in 21.1% of patients, with infections being the most common (7.9%).

Conclusion: Modular endoprosthetic reconstruction provides effective limb salvage with favourable functional and oncological outcomes. Complications remain a concern, highlighting the need for continued advancements in surgical techniques and prosthetic design.