Design of Mouth Dissolving Films of Polysaccharide Polymeric Combination

Abstract

The oral route is one of the most popular ways to administer drugs since it is patient-acceptable, safe, and easy to administer. Oral solid dose forms are available for about 60% of conventional dosage forms. For patients with illnesses including abrupt episodes of allergy reactions or coughing, as well as bedridden, emetic, pediatric, and geriatric patients, oral dissolving strips and films are helpful. Psychosis is a condition marked by convulsions, dementia, and hallucinations. In order to reduce the chance of irreversible brain injury, prompt care is necessary. The primary treatment approach for psychosis is still pharmacotherapy using anti-psychotic medications. Anti-psychotic medication formulation as an orally dissolving strip, which must be applied to the patient's tongue without swallowing in order to administer the dose, would greatly simplify dosage administration and increase patient compliance. Therefore, the objective of this effort was to design, create, and describe anti-psychotic medication mouth dissolving films. The core of an oral dissolving film is often composed of a plasticizer, a polymer that forms the film, or a combination of polymers that give the film the essential elasticity and shape.