A case series describing multisystem inflammatory syndrome associated with acute renal injury in pediatric sars-cov-19 infection.

Abstract

BACKGROUND: MIS-C (Multisystem inflammatory syndrome in children), is seen post COVID-19 infection with variable patho-physiology and symptoms. Acute kidney injury (AKI) is found to be a common feature in primary COVID-19 infections in adults, but it’s presentation in MIS-C has been rarely described & studied. We first described the 2019 novel coronavirus infection in 10 children occurring in IMS & SUM Hospital,Bhubaneswar, Odisha areas in India. The coronavirus diseases in children are usually mild and epidemiological exposure is a key clue to recognize paediatric case. Prolonged virus shedding is observed in respiratory tract and faeces at the convalescent stage [1].We present a series of 8 critically ill children with multisystem inflammatory syndrome with AKI. Key findings of this syndrome include fever, diarrhoea, shock, and variable presence of rash, conjunctivitis, extremity oedema, mucous membrane changes with acute kidney injury.