Anaesthetic Management of a case of Hereditary spherocytosis posted for Laparoscopic Cholecystectomy and Splenectomy: A Case report:

Abstract

Hereditary Spherocytosis (HS), a non-immune hemolytic anemia, results from red blood cell (RBC) transmembrane protein abnormalities. Surgical management, like laparoscopic cholecystectomy and splenectomy, poses challenges due to altered liver function and chronic hemolysis. A 20-year-old female with known HS underwent laparoscopic cholecystectomy and splenectomy. Preoperative assessment revealed blood transfusion history, altered liver function, and anemia. Examination showed pallor, icterus, and hepatosplenomegaly. Laboratory findings indicated microcytic hyperchromic RBCs and elevated bilirubin. Anesthetic management involved premedication, induction, and intraoperative monitoring, with attention to hemodynamic stability. Anesthetic management in HS patients undergoing surgery requires understanding pathophysiology and complications. Multidisciplinary collaboration and meticulous perioperative care are essential for optimal outcomes.