Comprehensive Phytochemical Profiling and Assessment of Antioxidant and Anti-inflammatory Activities of Manila Tamarind (Pithecellobium dulce) Extracts: Qualitative and Quantitative Analysis

Abstract

 BACKGROUND: The bioactive constituents extracted from different sections of the plants are used as therapeutic drugs in alternative medicine for treating diseases. The present study was intended to evaluate the chief phytochemicals present in PITHECELLOBIUM dulce, which was called Manilla tamarind, and its antioxidant and anti-inflammatory property.

METHODS: Aqueous extracts of Manilla tamarind was prepared in various fraction based on their polarity and screened for their major bioactive compounds. Their anti-oxidant property was evaluated by the phosphomolybdate assay and the anti-inflammatory property was evaluated by invitro percentage inhibition of protein denaturation.

RESULTS: Qualitative screening of aqueous extracts of Pithecellobium dulce in various concentrations ensured the presence of alkaloids, saponins, terpenoids, etc. Quantitative analysis of percentage inhibition of protein inhibition showed 92.5% inhibition and positive results on antioxidant properties.

CONCLUSION: The obtained results showed the presence of various phytochemicals and their various property (i.e.) both anti-oxidant and anti-inflammatory implying they have natural therapeutic potential and can be consumed for improving health status.