Evaluation of Antimicrobial Efficacy of Tinospora Cordifolia Extract on Drug Resistant Pathogens

Abstract

The lightning-fast raise in drug-resistant pathogens represents an urgent threat to all over the world health, requiring the creation of innovative tactics to counter these formidable adversaries. In particular, the effectiveness of novel antimicrobial agents in the face of rising antibiotic resistance is examined in this study, which focuses on the assessment of antibacterial activity against drug-resistant pathogens.A thorough and interdisciplinary strategy that combined microbiological and molecular methods was used to achieve this. A range of in vitro susceptibility tests, such as determining minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) for different antibacterial compounds were performed on drug-resistant strains of bacteria that were isolated from clinical samples.

These investigations yielded significant findings about the genetic factors that influence antibiotic resistance as well as possible targets for completely novel antibacterial drugs. Using a panel of drug-resistant strains, the antibacterial activity of new compounds was assessed. These strains included multidrug-resistant strains resistant to Carbapenem and extended-spectrum β-lactamase (ESBL) producers. Using a variety of in vitro tests, the susceptibility of these pathogens to experimental antimicrobial agents was evaluated.

Promising antimicrobial plant components that are active against drug-resistant pathogens are revealed by the study's findings. These substances show promise in treating difficult infections that are resistant to drug.  In order to conclude, assessing antibacterial activity against pathogens that are resistant to drugs is an essential task in the battle against antibiotic resistance. This study highlights the value of multidisciplinary strategies that combine drug development, genomics, and microbiology to find and assess viable remedies for this escalating public health emergency. The results of this study highlight the significance of ongoing research and innovation in this field and support ongoing efforts to create efficient treatments for drug-resistant infections.