Estimation of Serum Urea, Creatinine, And Electrolytes in Corona Virus Disease 2019 Covid-19 Positive Patients

Abstract

Introduction: China saw the outbreak of Coronavirus Disease 2019 (COVID-19), an emerging infectious disease with an unknown etiology, during the winter of 2019. This unidentified virus was later identified and given the name severe acute respiratory syndrome.  second coronavirus (SARS-CoV-2). More data point to the association between renal dysfunction and coronavirus disease 2019 (COVID-19). Uncertainty surrounds the relationship between renal dysfunction brought on by the SARS-CoV-2 virus and prognosis.

Objectives: The objectives center around recognizing the impact of COVID-19 on renal function, advocating for continuous monitoring, and proposing specific blood markers as indicators for predicting patient outcomes.

Methods: 160 hospitalised COVID-19-positive patients were enrolled in the current study, of which 80 were assigned to Group I — COVID-19 patients who were critically sick (severe cases), and 80 to Group II — COVID-19 patients who were not critically ill (mild and moderate cases). Using the Architect system (201837-110) to measure serum urea and creatinine levels, data were reported as mg/dL

Results: In the current investigation, group I samples demonstrated a highly significant increase in serum urea, creatinine, and Sodium compared to group II samples When comparing critically sick COVID-19 patients (severe cases) to non-critically ill COVID-19 patients (mild and moderate cases), there was no discernible difference in the mean difference of serum potassium.

Conclusions: Impaired kidney function, hyponatremia, and developing kidney damage should notify clinicians during COVID-19 patient care. In clinical practice, serum electrolytes, as well as serum urea and creatinine, can be utilized to predict Covid-19 patient survival.