Assessment of Knowledge and Understanding of Tissue Chip Mimicry’s Impact on Dental Practice among Dental Practitioners: A Questionnaire based Study

Abstract

Background:Organ-on-chips have revolutionized various fields of research, including dentistry. These chips can be used to model oral tissues and study the interactions between teeth, gums, and other oral structures. By creating a realistic in vitro model of the oral cavity, researchers can investigate oral diseases, test new dental materials, and develop more effective treatments.These chips allow researchers to simulate the interactions between dental materials and oral tissues, providing insights into their long-term effects and potential risks.

Aims: The objective of this assessment study was to collect information about the knowledge and understanding of tissue chip mimicry’s impact on dental practice among dental practitioners pan India.

Materials and Methods: A cross-sectional,self administered questionnaire-based study was conducted among 421 dental practitioners pan India. A pre-validated closed-ended questionnaire with 19 questions was given to collect the data under two headings: (a) knowledge of dental practitioners on 2D and 3D cell culture and (b) understanding of tissue chip mimicry and its role in dentistry.  Results have been presented in numbers and responses for each of the questions have been reported as percentages.

Result:It is evident from the study that  tissue chip technology is relatively new and to date, the emerging technologies have not found their way into widespread use.

Conclusion:Conducting long-term studies on organ-on-chip systems can provide valuable insights into the long-term effects of dental treatments and interventions. Encouraging collaboration between dentists, bioengineers, and material scientists can lead to innovative advancements in organ-on-chip technology for dental applications.Developing patient-specific organ-on-chip models can enable personalized dental treatments and interventions, improving treatment outcomes and patient satisfaction.