Ethnopharmacological Investigations of Argemone Mexicana for Psoriasis Management using Molecular Techniques.

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Omar Faruque, Vrushali Bhalchim, J Swaminathan, Praveen Kumar Ashok, Pankaj Nainwal, Soma Das, Umama Yezdani, Simachal Panda

Abstract

Objective: Psoriasis's an autoimmune disease, which is causing the body to attack itself. It'll be in the 30 to 65 age group. This disease affects over 100 million people in the world. The aim of the study is to provide more efficient and safer treatment for patients with this disease.


Methods: In a random selection of individuals from Hyderabad, Telangana. the potential study has been conducted. Patients with psoriasis of different ages were randomly selected and formulation made with the plant extract was applied twice a day externally on the marks for 3-4 months.


Result:


We've looked at around a dozen patients in each city of Hyderabad. Physical examination and their past illnesses and health history have confirmed this condition. This study was used for 6 months, during which cream has been applied on the area concerned 2 times a day. It was found that the marks disappeared completely in about 8 of the 12866.6%) patients in Hyderabad, and in another 2 of the 12866.6%) patients there was a mild response and 2 of the 12866.6%) patients had a mild response. of them showed no response to the formulation. Whereas in Hyderabad around 6 of 12(50%) showed complete cure, 4 of 12(33.3%) with mild response and 2 of 12(16.6%) with no response to the drug. No side effects were observed in any of the age groups.


Conclusion:


Utilising a compound derived from argemone Mexicana leaves reduced psoriasis. Patients across all age groups reacted to this formulation in varied ways. Younger patients and those whose sickness had just recently begun to manifest responded very well to the treatment. Greater favourable response was observed in Warangal than in Hyderabad, indicating that environmental variables can influence illness management and therapy. However, no adverse effects were observed in any of the age groups or cities, 

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