Potential inhibitors of xanthene derivatives by molecular docking study

Abstract

In the present study, we prepared new xanthene derivatives for the conventional method, and the derivatives are confirmed by the IR, NMR and mass spectral techniques. In the present scenario, numerous people have been affected by the virus for the past two years in the world. Xanthene derivatives in prediction of molecular docking for new compounds and docking studies were performed to investigate the hypothetical binding mode of the target compounds. The lowest binding energy like -5.43, -5.57, -6.25, -5.99 and -5.47 kcal/mol confirmed by protein binding to the molecules. The hydrogen bonding interactions are confirmed by suitable binding confirmation for the docking.