"Analysis of Antibiotic Susceptibility Tests for Bacterial Strains Linked to Urinary Tract Infections in Pregnant Women"
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Abstract
Urinary tract infections (UTIs) pose a significant health concern for pregnant women, especially in underdeveloped regions, being a primary cause of pregnancy-related illnesses globally. Causative agents include E. coli, Klebsiella species, Staphylococcus aureus, Staphylococci, Proleusmirabilis, Enterococcus species, Pseudomonas aeruginosa, Enterobacter species, streptococci, and Citrobacter species. The prevalence of UTIs among pregnant women ranges approximately from 13% to 18%. Bacterial identification revealed both gram-positive and gram-negative forms, with gram-negative bacteria accounting for 85% and gram-positive for 15%. Notably, E. coli emerged as the most frequently found bacterium in this study.Antimicrobial susceptibility testing demonstrated high resistance among these isolates to nitrofurantoin, ciprofloxacin, and gentamicin, while displaying greater sensitivity to antibiotics like amoxiclav and cefuroxime. Additionally, pregnant women with asymptomatic UTIs, caused by Klebsiella pneumonia, E. coli, Proteus mirabilis, Acinetobacter baumanni, Pseudomonas aeruginosa, Staphylococcus arlettae, and Enterococcus faecalis, showcased resistance to multiple drugs.
Understanding the prevalence of these isolates in urine samples and their resistance profiles becomes crucial in guiding empirical treatments, aiming to minimize adverse effects on pregnant women. Ongoing research endeavors focus on combatting UTIs in pregnant women, particularly addressing drug resistance through novel technologies and identification methods to manage these infections effectively.