An In-Vivo Study Comparing Efficacy of Mouthwash Containing Adhatoda Vasica and Camellia Sinensis on Rate of Tooth Movement in Orthodontic Patients.

Abstract

Introduction: A. vasica possessing a rich amount of phytochemicals can be of use in this area of orthodontics. However, its antioxidant and anti‑inflammatory properties can be used to predict its effect on bone. Its effects are seen in protecting bone in arthritis. A. vasica has pyrroloquinazoline, which suppresses macrophage production. Osteoclasts are macrophage‑derived and inhibition of macrophages would lead to a reduction in osteoclasts, causing a modification of bones amd may affect number of osteoblasts, osteoclasts and fibroblasts. Therefore, in the future, OTM‑specific studies on A. vasica have to be carried out. Green tea, Camellia sinensis, is one of the most popular drinks the world over. Its green color and natural micronutrients are preserved by steaming the freshly harvested leaves to destroy the enzymes responsible for breaking down the color pigments in the leaves that allows the tea to maintain its green color. Green tea contains polyphenols and catechins which have antioxidant, anti-diabetic, anti-mutagenic, anti-viral, anti-bacterial, and anti-inflammatory effects. The anti-Inflammatory effect of green tea is attributed to inhibit the effects of COX-2.

Objective: To evaluate efficacy of Adhatoda Vasica & Camellia sinensis on rate of tooth movement in orthodontic patients.

Materials and Method: The study sample consisted of 30 eligible participants aged 18 –25 years ongoing orthodontic treatment. They were divided into control, (green tea) Camellia Sinesis, and A. vasica groups, with 10 subjects per group. Orthodontic force was carried out using a orthodontic bracket and open coil spring with strength of 50 grams. Subjects in the groups will be instructed to rinse with A. vasica and Camellia sinesis solution twice a day for 30 days (prepared by soaking 10 g A.Vasica powder in 200ml hot water and 10g of Camellia Sinesis for overnight and straining the water the next day) The values will be recorded and statistically analyzed at baseline 15th and the 28th day.

Results: A. Vasica mouthwash may be found to have significantly increased osteoclast counts. The osteoblastic activity notably increased on the 28th day (p-value < 0.001). All measured outcomes demonstrated notable effects, with the greatest observed for the A. vasica group, followed by the Camellia Sinesis group, and finally, the control group.

Conclusion: A.vasica mouthwash can be used effectively to increase orthodontic tooth movement by significant decrease in osteoclastic activity.