The Metabolic - Sleep Nexus: Anthropometric and Polysomnographic Profiles of PCOS Women with and without Syndrome Z
Main Article Content
Abstract
Background
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder associated with metabolic dysfunction and sleep disturbances. Obstructive Sleep Apnea (OSA) frequently coexists with metabolic syndrome, forming a high-risk entity known as Syndrome Z, which significantly increases cardiometabolic risk
Aim:
To evaluate and compare anthropometric and polysomnographic characteristics in women with PCOS with and without Syndrome Z
Methodology:
A cross-sectional observational study was conducted among 77 women diagnosed with PCOS. All participants underwent anthropometric assessment, metabolic evaluation, and overnight polysomnography. Statistical analysis was performed using independent t-test and Chi-square test
Results:
OSA prevalence was 49.4%. Syndrome Z was present in 27.3% of participants. Women with Syndrome Z had significantly higher BMI, central obesity indices, insulin resistance, and adverse lipid profiles. Polysomnography showed significantly higher AHI, ODI, and arousal index, with reduced sleep efficiency (p < 0.001)
Conclusion:
Syndrome Z is highly prevalent in PCOS and is associated with severe metabolic and sleep disturbances. Early identification and integrated management are essential