Associations Between Serum Phthalates and Thyroid Hormone Levels in Long-Term Plastic Using Female Volunteers

Abstract

Introduction: Phthalates are a class of industrial chemicals that are often employed as softeners and plasticizers in a variety of commercial items, such as toys, furniture, medical equipment, food packaging materials, and cosmetics. Phthalates can be inhaled, consumed, or come into contact with the skin. Phthalates undergo quick metabolism to produce their corresponding monoesters and oxidative metabolites, which are then eliminated in the urine and faeces.
Objectives: This study investigates the effect of serum phthalate on Thyroid hormones in women volunteers using plastics for short and long-term.
Methods: 2500 female participants in the reproductive age range of 20–45 years were given questionnaires. Women participants are divided into two groups based on their age and level of exposure to plastic products: Group I is for short-term exposure to plastics, aged 20–32, and Group II is for long-term exposure to plastics, aged 33–45.