In Vitro Antibacterial Activity and Phytochemical Profiling of Flower Extracts from Hibiscus rosa-sinensis, Cassia auriculata, Clitoria ternatea, and Catharanthus roseus as Potential Natural Therapeutic Agents Against Pathogenic Bacteria

Abstract

Introduction: Medicinal plants are abundant in bioactive compounds with significant therapeutic potential, making them a cornerstone for drug discovery and alternative therapies. Hibiscus rosa-sinensis, Cassia auriculata, Clitoria ternatea, and Catharanthus roseus have been traditionally used in medicine and are known for their antibacterial properties, offering promise in combating antibiotic-resistant bacteria.
Objectives: This study aims to evaluate the in vitro antibacterial efficacy of flower extracts from these plants and identify their bioactive compounds to support the development of novel therapeutic agents for bacterial infections.
Methods: Standard microbiological techniques were employed to assess the antibacterial activity of the flower extracts against pathogenic bacteria. Phytochemical analyses were conducted to profile the bioactive compounds present in the extracts, integrating traditional knowledge with modern scientific approaches.
Results: The extracts demonstrated notable antibacterial activity against pathogenic bacteria, underscoring their potential as natural remedies. Phytochemical profiling revealed diverse bioactive compounds that could serve as the basis for developing novel antibacterial agents.
Conclusion: The findings validate the efficacy of these medicinal plant extracts in combating bacterial infections, offering a promising avenue to address the global challenge of antibiotic resistance. The study highlights the importance of leveraging traditional knowledge and scientific innovation to explore plant-based solutions for healthcare challenges.