Antimicrobial Activity of Compounds Produced by Endophytic Fungi Isolated from Aloe Vera Roots

Abstract

Endophytic fungi are an important source of biologically active secondary metabolites, including novel antimicrobial agents. This study aimed to isolate endophytic fungi from the roots of Aloe vera, characterize isolates morphologically, obtain fungal crude extracts and partially purified fractions, and evaluate their antibacterial and antifungal activity against a panel of wound attacking pathogens (Escherichia coli, Klebsiella, S. aureus, and E faecalis). using solid-medium agar diffusion, broth Mueller Hinton. These results confirm that Aloe vera root endophytes are a promising source of antimicrobial natural products and warrant further chemical purification and structure elucidation.