Association of Serum Leptin with Dyslipidemia in Patients with Preeclampsia

Abstract

Introduction: Leptin is a protein generated from adipose tissue and involved in metabolism. Leptin has recently been linked to preeclampsia, in addition to other indicators for the diagnosis. This study's aims to evaluate the serum leptin levels with blood sugars and dyslipidemia in preeclamptic women and controls.

Objectives: This study's aims to evaluate the serum leptin levels with blood sugars and dyslipidemia in preeclamptic women and controls.

Methods: A cross-sectional study was conducted in the Department of Obstetrics and Gynecology. A total of 120 pregnant women with and without preeclampsia were included in the study group. Serum leptin was estimated by leptin ELISA kit.

Results: The preeclampsia groups had higher levels of leptin than the control groups and these levels were significantly associated with BMI, blood pressure and dyslipidemia (P = 0.001**).

Conclusions: This study concludes the association of high serum leptin levels with preeclampsia and determination of serum leptin can be used as a diagnostic marker in preeclampsia in addition to other conventional biomarkers.