Extraction, Evaluation and A Comparative Study of Mimosa Pudica Seed Mucilage with Trigonella Foenum Graecum and Flax Seed Mucilage

Abstract

Objectives: The aim of this research article is to provide a brief knowledge about the comparative study of the mucilage extracted from the seed of Mimosa pudica with the mucilage extracted from Trigonella foenum graecum (Fenugreek) and Flax seed. Nowadays, industrialist are likely to use natural polymers due to various problems associated with drug release and side effects with synthetic polymers.  Methods: Mucilage from different seed were extracted and isolated by conventional method using ethyl alcohol and acetone as a precipitating solvent. The extracted mucilage were evaluated by means various organoleptic properties, phytochemical properties, swelling index, loss on drying and micromeritics. Results: The extracted mucilage were pale yellow to brown in color, % yield of all mucilage were in the range of 29.12%w/w to 33.51%. Phytochemical tests were done for all mucilage confirmed the absence of alkaloids and glycosides. The pH of 1- 5% w/v aqueous dispersion of all three samples of mucilage was found between5.5 to 7.1. The solubility and swelling index of all mucilage also found good.  All the values of micromeritics properties were found within the range. Conclusion: The present study suggests that the extracted mucilage from all the seed will be useful as an additives for oral muco-adhesive drug delivery systems as per the results of phytochemical and physicochemical tests indicated the suitability of mucilage for tablet dosage form as well as a suspending agent for suspension due to its swell able properties, weakly acidic pH and viscous in nature.