Association Between Poor Sleep Quality and Higher Total Cholesterol in South Indian Adults Undergoing Health Check-up: A Cross-Sectional Study

Abstract

Introduction:

The prevalence of diseases associated with metabolic syndrome are on the rise(diabetes, hyperlipidemia, obesity) and poor lifestyle choices such as sleep quality are associated with an increase in the prevalence of those diseases. Our study aimed to evaluate the relationship between the quality of sleep and cholesterol profile of individuals.

Materials and Methods:

PSQI(Pittsburgh Sleep Quality Index) obtained from a questionnaire as well as serum cholesterol levels and personal information such as gender and age.252 patients were given the PSQI questionnaire in which 198 patients were chosen after reviewing the inclusion and exclusion criteria. Logistical regression and multivariate linear regression was done on the data obtained.

Results:

Statistically significant correlation was obtained between poor sleepers and increased serum cholesterol levels when adjusted for age and BMI. In the multivariate linear regression, serum cholesterol increases by approximately 8.3-10.2 mg/dL.

Conclusion:

Although there is a correlation between sleep quality and serum total cholesterol, identifying confounders and adjusting for their effect can further our knowledge and understanding of the biochemical effect on quality of sleep and vice versa.