Febrile Seizure in Hospital Based Childrens; A Case Control Study

Abstract

Background : Febrile seizure (FS) or febrile convulsion (FC) is the most common neurological disease. It commonly occurs among children aged 6 months to 5 years, with the global incidence rate of 2 – 5 %  .

Objective: The main objective of this case study to find prevalence among hospitalized children of a tertiary care teaching hospital

Methodology: This hospital-based, case-control study was conducted at the Department of Paediatrics of a tertiary care teaching hospital, R Statistical Software is used for this study for the; A & B Group.

Result and conclusions: In the current study, the incidence of IDA and ZD was higher in children with FC (cases) compared to children without FC (controls). ZD was found among 86% of the cases and IDA was found among 73% of the case, indicating that hypozincemia and IDA are predisposing factors to FS. Significantly higher number of children in cases had lower serum ferritin levels (Iron deficiency) compared to control. As RDW can be used to distinguish between simple and complex type of seizure. Higher number of the children with FC had RDW of >15 compared to controls, indicating a possible relationship between RDW and FC. The final conclusion to this study is that deficiency of zinc and iron among children of 6 – 60 months is proposed as a modifiable risk element for FS. Early detection and timely correction of micronutrient deficiency (iron and zinc) might be helpful in preventing FS. However, long term randomized controlled trials with a large sample size are needed to make it as a treatment protocol.