Association of Taila Bindu Pariksha Patterns with Clinical Severity Indicators in Benign Prostatic Hyperplasia: A Cross-Sectional Observational Pilot Study

Abstract

Introduction: Taila Bindu Pariksha (Oil Drop Test or TBP), a component of Mutra Pariksha, is described in classical Ayurveda texts as a method for understanding Sadhya (curable) - Asadhyata (incurable) prognosis of disease. Benign Prostatic Hyperplasia (BPH) is a prevalent urological disorder characterised by urinary obstruction leading to Lower Urinary Tract Symptoms (LUTS). The evaluation of BPH, such as Transabdominal Ultrasonography (TAUS), the International Prostate Symptom Score (IPSS), and Prostate-Specific Antigen (PSA), demonstrates variable sensitivity and specificity, highlighting the need for a revalidated Prognostic approach. The present study aims to re-evaluate and validate the prognostic significance of TBP in patients with BPH.

Methods: A cross-sectional observational pilot study was conducted at the institutional OPD, enrolling 30 men aged 40–85 years with BPH. Participants were selected based on predefined inclusion and exclusion criteria.  Early morning midstream urine samples were collected and evaluated using TBP, TAUS, IPSS and PSA were assessed. Comparison and Associations were analysed using statistical tests, including t-tests, Kruskal–Wallis, Chi-square, and Fisher's exact test.

Results: TBP direction and spread were significantly associated with TAUS and IPSS, while shape and PSA showed no significant effect; TBP patterns were influenced predominantly by Vata dosha.

Conclusions: TBP parameters such as direction and spread showed significant associations with TAUS and IPSS, indicating their prognostic relevance in assessing urinary disorders. While shape and PSA exhibited no significant effect. Overall, TBP patterns were predominantly influenced by Vata dosha, suggesting that functional disturbances governed by Vata play a major role in the pathophysiology of urinary alterations.