Catalytic synthesis of 1-benzyl-4-fluoro-2- phenyl-1 H- benzo [d] imidazole: Dual applications in sensor and antimicrobial properties

Abstract

Binding interaction of 1-benzyl-4-fluoro-2-phenyl-1H-benzo[d]imidazole (BFPB) functionalized ZnO nano flowers have been studied by absorption and fluorescence spectral studies. Functionalization of BFPB with ZnO nano flowers results agglomeration of nanoparticles shown by SEM images. BFPB was synthesized using ZnO catalyst. The remarkable features of this nanocatalyst are high productivity, short reaction time, green reaction and diverse substrate applications. Synthesized BFPB was characterized by proton NMR, carbon NMR, mass spectral studies and elemental analysis. Binding of BFPB enhance the fluorescence intensity of ZnO nano flowers. BFPB adsorbs on the surface of ZnO nano flowers which induce the electron transfer. BFPB is highly effective against S.aureus and S.typhi, for antibacterial studies and it was more active against A.flavus and C.albicans for antifungal studies compared to the standard drug.