The Role of Novel Biomarkers in Predicting Acute Kidney Injury in Critically Ill Patients

Abstract

Critically ill patients are frequently affected by the common and possibly fatal illness known as acute kidney injury (AKI). To improve patient outcomes and lower healthcare costs, early detection and prediction of AKI are crucial. The existing gold standards for detecting AKI, such as serum creatinine and urine output, frequently fall short in terms of sensitivity and specificity, which causes interventions to be postponed and patient care to be less than ideal. The expanding landscape of new biomarkers for predicting AKI in critically ill patients is examined in this review paper.

Promising biomarkers with improved accuracy and early detection capabilities have been discovered thanks to recent advances in molecular and biochemical research. Healthcare professionals may be better able to spot patients at risk of AKI by assessing these unique indicators, enabling quick intervention and customized treatment regimens.

The present state of biomarker research in AKI prediction is thoroughly discussed in this review paper, along with significant advancements, difficulties, and possible therapeutic applications. We want to clarify the clinical significance and potential uses of emerging biomarkers for detecting AKI in critically unwell patients as soon as possible.