Some Biochemical Parameters and Level of Preptin in Newly Diagnosed Type 2 Diabetic Women Patients in Tikrit City

Authors

1 Department of Biology, College of Science, Tikrit University, Tikrit, Iraq

2 Department of Prostheses, Al-Dour Technical Institute, Northern Technical University, Saladin, Iraq

Abstract

A chronic disease categorized by high blood sugar called diabetes mellitus (DM), Its prevalence is rapidly increasing all over the world. Peptin is a peptide produced by cells of pancreas. It plays as a physiologic enhancer of glucose-mediated insulin secretion. There, the current study aimed to note differences in the levels of newly diagnosed patients with T2DM controls. This study was directed at Salah el-Deen medical Clinic in Tikrit city and included women from Salah al-Din Hospital in Tikrit in the period since Feb to Jul 2020, 40 newly diagnosed patients T2DM and 40 healthy elderly women. Preptin, Hba1c, fasting blood glucose (FBS), blood urea (BU), and serum creatinine levels will be examined. The present study discovered a significant rise in Preptin (362.460.01pg
ml-1), Hba1c (8.82.7 %), FBS (205±25.7mg dl-1), BU (20.71 ±4.3 mmol l-1), and creatinine (1.1±0.2mg dl-1) in female T2DM patients compared to the control group (222.8±30.7pg ml-1, 4.6±1.3 %, 99±15. The observed link between preptin level and diabetes mellitus a suggests that this peptide may play a role in the pathogenesis of DM, which may be of particular interest to a group DM that constitutes  a major public health problem.

Keywords


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Volume 12, Issue 2
May 2022
Pages 179-182
  • Receive Date: 29 March 2021
  • Revise Date: 20 February 2022
  • Accept Date: 25 June 2021
  • First Publish Date: 20 February 2022