Synthesis of New Glycine Cephalexin Condensed Polymer as Peptide Biopolymer for Controlled Release of Cephalexin

Authors

1 College of Pharmacy, Al-Mustansiriyah University, Baghdad, Iraq

2 Department of Chemistry, College of Science, University of Misan, Maysan, Iraq

Abstract

A new peptide-based polymer was synthesized via polymerization of cephalexin acid chloride with glycine acid chloride with molar ratio 1:1 in condensed polymer solution. This Glycine Cephalexin peptide biopolymer was characterized by different analyses of UV, FT-IR and 1H NMR spectroscopy. Also, physical properties of new synthesized Glycine Cephalexin peptide biopolymer were studied with measurement of its intrinsic viscosity at 30°C, swelling percentage in water and studying drug release in pH 4-10 at 37°C.

Keywords

References

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Journal of Chemical Health Risks
Volume 11, Issue 3
July 2021
Pages 339-344

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History

  • Receive Date: 25 May 2021
  • Revise Date: 15 September 2021
  • Accept Date: 20 August 2021
  • First Publish Date: 20 August 2021

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