Evaluation of In-vitro Antimicrobial Activity of some Newly Synthe-sized2-amino-3-phenylsulfonyl-4-aryl-4H-benzo[h]chromens Derivatives

Document Type : Original Article


1 Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran

2 Department of Resin and Additives, Institute for Color Science and Technology, P.O. BOX: 16765-654, Tehran, Iran


In this study, some chromens derivatives were synthesized as mentioned in our previous report.The synthesized compounds were evaluated for their antibacterial effect against three different bacterial species, using Disk Diffusion Agar test and microdilution broth (MIC) method against the S. aureus, E. coli, P. aeruginosabacterias according to the National Committee for Clinical Laboratory Standards (NCCLS) recommendations. The results indicated that 4-nitro compound has considerable antibacterial activity against S. aureusbacteria. Moreover, compound 3-chloro has antibacterial properties  againstE. coli standard strain and none of 4H-Chromens derivatives have antibacterial effect on P. aeruginosa  strains.


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Volume 9, Issue 1
March 2019
Pages 69-74
  • Receive Date: 05 October 2018
  • Revise Date: 12 December 2018
  • Accept Date: 01 January 2019
  • First Publish Date: 01 March 2019