Response of Leptin and C-reactive Protein Serum Levels to 12 Weeks Moderate Intensity Aerobic Exercise in Obese Men


1 Department of Exercise Physiology, Faculty of Physical Education, University of Urmia, Urmia, Iran

2 Department of Physiology, Urmia University of Medical Science, Urmia, Iran


The aim of this study was to investigate the effect of 12 weeks moderate intensity aerobic exercise on leptin and C-reactive protein serum levels in obese men. The study was conducted in Urmia- Iran in 2015. Twenty-four obese men with an aged range 40-50 yrs. were enrolled into the study. Subjects were randomized to one of 2 groups exercise (n=12) and control groups (n=12). The exercise group performed aerobic exercise training up to 50-70 % heart rate reserve, three times a week for 12 weeks. Leptin and CRP serum level was measured by ELISA method before and after the 12 weeks. After 12 weeks exercise training, leptin and CRP serum level in the exercise group compared to the control group, were decreased significantly (P<0.05). To sum up, 12 weeks moderate intensity aerobic exercise in the reduction of CRP and leptin concentration had a prominent role that might be effective in reducing weight and improving cardiovascular risk factors.


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Volume 7, Issue 1 - Serial Number 1
January 2017
Pages 33-37
  • Receive Date: 01 January 2017
  • Revise Date: 07 December 2019
  • Accept Date: 29 October 2018
  • First Publish Date: 29 October 2018