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Akhlaghi, H., Akhlaghi, S., Mahdavi, B., Rezaei, H. (2015). Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity. Journal of Chemical Health Risks, 5(2), -. doi: 10.22034/jchr.2015.544100
Hashem Akhlaghi; Sedighe Sadat Akhlaghi; Bhnam Mahdavi; Hasan Rezaei. "Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity". Journal of Chemical Health Risks, 5, 2, 2015, -. doi: 10.22034/jchr.2015.544100
Akhlaghi, H., Akhlaghi, S., Mahdavi, B., Rezaei, H. (2015). 'Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity', Journal of Chemical Health Risks, 5(2), pp. -. doi: 10.22034/jchr.2015.544100
Akhlaghi, H., Akhlaghi, S., Mahdavi, B., Rezaei, H. Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity. Journal of Chemical Health Risks, 2015; 5(2): -. doi: 10.22034/jchr.2015.544100

Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity

Article 5, Volume 5, Issue 2, Summer 2015  XML PDF (279.08 K)
DOI: 10.22034/jchr.2015.544100
Authors
Hashem Akhlaghi email 1; Sedighe Sadat Akhlaghi2; Bhnam Mahdavi3; Hasan Rezaei4
1Department of Basic Sciences, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran
2Internist Department of Nephrology, Shahid Beheshti Medical University, Tehran, Iran
3Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran
4Traditional Medicine Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran
Receive Date: 26 April 2015,  Revise Date: 17 September 2019,  Accept Date: 29 October 2018 
Abstract
: In this study, the essential oil obtained by hydrodistillation of the aerial parts of Sclerorhachis platyrachis (Boiss.) Podlech ex Rech. f. (Compositae), growing wild in Sabzevar, Khorasan Razavi Province (Iran), was analyzed by GC and GC/MS. The total yield of volatiles was 0.38% (w/w). Sixty- three compounds representing 89.2% of the aerial parts oil were identified.  The main components of the oil were β-pinene (17.5%) and γ-terpinene (15.4%). The oil was rich in monoterpenoids, and among them, monoterpene hydrocarbons (48.7%) predominated over oxygenated monoterpenes (11.8%). The total flavonoid content of different extracts of the plant was in the range 52.4-172.3 mg/g, with the maximum amount being in the methanol extract. The antioxidant activities of the extracts were also measured based on radical scavenging activity of antioxidants using the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) method. The results showed that IC50 values of extracts of S. platyrachisare higher than for the standard synthetic antioxidants, BHT, ascorbic acid and gallic acid.   
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