Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity

Authors

1 Department of Basic Sciences, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran

2 Internist Department of Nephrology, Shahid Beheshti Medical University, Tehran, Iran

3 Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran

4 Traditional Medicine Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran

Abstract

: In this study, the essential oil obtained by hydrodistillation of the aerial parts of Sclerorhachis platyrachis (Boiss.) Podlech ex Rech. f. (Compositae), growing wild in Sabzevar, Khorasan Razavi Province (Iran), was analyzed by GC and GC/MS. The total yield of volatiles was 0.38% (w/w). Sixty- three compounds representing 89.2% of the aerial parts oil were identified.  The main components of the oil were β-pinene (17.5%) and γ-terpinene (15.4%). The oil was rich in monoterpenoids, and among them, monoterpene hydrocarbons (48.7%) predominated over oxygenated monoterpenes (11.8%). The total flavonoid content of different extracts of the plant was in the range 52.4-172.3 mg/g, with the maximum amount being in the methanol extract. The antioxidant activities of the extracts were also measured based on radical scavenging activity of antioxidants using the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) method. The results showed that IC50 values of extracts of S. platyrachisare higher than for the standard synthetic antioxidants, BHT, ascorbic acid and gallic acid.   

References

  1. Mozaffarian V., 2013. Identification of Medicinal and Aromatic Plants of Iran. Farhang Moaser Publisher, Tehran, 1st edit.
  2. Rechinger K.H., 1986. Sclerorhachis, in: Flora Iranica, Compositae No. 158. Edits., K.H. Rechinger and I.C. Hedge, P 47, Akademische Druck and Verlagsanstalt, Graz, Austria.
  3. Mozaffarian V., 1996. A Dictionary of Iranian plant names. Farhang Moaser Publischer, Tehran, 1st Edit., p 491.
  4. Aghajani Z., Masoudi S., Rustaiyan A., 2005. Volatile oils of Anthemis talyshensis A. Fedor and Sclerorhachis platyrachis (Boiss.) Podlech ex Rech. f. from Iran. J Essent Oil Res. 17 (4), 355-357.
  5. Kheyrabadi R., Habibi Z., Ng S.W., 2011. 2-{(1S,2S,4aR,8R,8aR)-8-Hydroxy-4a,8-dimethyl-1-[(2E)-2-methylbut-2-enoyloxy]perhydronaphthalen-2-yl}acrylic acid from Sclerorhachis platyrachis, Acta Crystallographica Section E, Structure Reports Online, 67, Part 10: pp. o2699.
  6. Habibi Z., Kheyrabadi R., Ghasemi S., Yousefi M., Ng S.W., 2012. A new sesquiterpenoid from Sclerorhachis platyrachis (Boiss.) Podlech ex Rech. f. Phytochemistry Letters. 5(4): 705-707.
  7. Adams R.P., 2007. Identification of Essential oil Components by Gas Chromatography/Mass Spectrometry. Allured Pub. Corp., Carol Stream, IL., USA.
  8. Singleton V.L., Orthofer R., Lamuela-Raventos R.M., 1999. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folinââ‚‌“Ciocalteu reagent. Meth Enzymol. 299, 152ââ‚‌“178.
  9. Mensor L.I, Menezes F.S., Leitao G.G., Reis A.S., Dos Santos T., Coube C.S., Leitao S.G., 2001. Screening of Brazilian plants extracts for antioxidants activity by use of DPPH free radical method. Phytother Res. 15, 127-130.
  10. Mohsen M.S., Ammar S.M.A., 2008. Total phenolic contents and antioxidant activity of corn tassel extracts. Food Chem. 112, 595-598.
  11. Amarowicz R., Pegg B.R., Rahimi-Moghaddam P., Bar B., Weil J.A., 2003. Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chem. 84, 551-562.
Journal of Chemical Health Risks

Volume 5, Issue 2
Summer 2015

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History

  • Receive Date: 26 April 2015
  • Revise Date: 18 January 2020
  • Accept Date: 29 October 2018

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