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Vaezi, G., Pourkazem, M., Toosi, F., Aliabadi, F. (2013). Effects Aerosol of Industrial Bleach and Detergent Mixture on Mucosa Layer and Lamina Mucosa Conjunctiva in Mice. Journal of Chemical Health Risks, 3(1), -. doi: 10.22034/jchr.2018.544014
Gh. Vaezi; M. Pourkazem; F. Toosi; F. Aliabadi. "Effects Aerosol of Industrial Bleach and Detergent Mixture on Mucosa Layer and Lamina Mucosa Conjunctiva in Mice". Journal of Chemical Health Risks, 3, 1, 2013, -. doi: 10.22034/jchr.2018.544014
Vaezi, G., Pourkazem, M., Toosi, F., Aliabadi, F. (2013). 'Effects Aerosol of Industrial Bleach and Detergent Mixture on Mucosa Layer and Lamina Mucosa Conjunctiva in Mice', Journal of Chemical Health Risks, 3(1), pp. -. doi: 10.22034/jchr.2018.544014
Vaezi, G., Pourkazem, M., Toosi, F., Aliabadi, F. Effects Aerosol of Industrial Bleach and Detergent Mixture on Mucosa Layer and Lamina Mucosa Conjunctiva in Mice. Journal of Chemical Health Risks, 2013; 3(1): -. doi: 10.22034/jchr.2018.544014

Effects Aerosol of Industrial Bleach and Detergent Mixture on Mucosa Layer and Lamina Mucosa Conjunctiva in Mice

Article 1, Volume 3, Issue 1, Winter 2013  XML PDF (224.89 K)
DOI: 10.22034/jchr.2018.544014
Authors
Gh. Vaezi email 1; M. Pourkazem2; F. Toosi2; F. Aliabadi2
1Associate professor, Damghan Branch, Islamic Azad University, Damghan , Iran
2Department of Biology, Faculty of Science, Damghan Branch, Islamic Azad University, Damghan , Iran
Receive Date: 19 August 2013,  Revise Date: 22 October 2019,  Accept Date: 29 October 2018 
Abstract
Today bleach and detergents are being frequently used and some people use their mixture for more cleaning. Because of chemical interaction of bleach and detergent, chlorine gas was released and thereby it could be dangerous for human health. This study examined the effects of exposed toxic mixture of bleach and detergent on the Mucosa layer and Lamina mucosa conjunctiva in the mice. In this study, 42 adult male mice NMRI race weighing 35-40 gr and from age 8 to 10 weeks were divided into 6 experimental groups and one control group. Experimental groups 1-2-3 with the use of chamber, the exposed 20 minutes were exposed to spray the amount 1 cc of mixture of bleach and detergent by nebulizer. Experimental groups 4-5-6 were for 35 minutes to inhale the same amount of material. Mice killed at 24-48-72 hours after exposed and the Mucosa Layer and Lamina mucosa conjunctiva tissue was studied pathology. In the study of microscopic sections prepared of mouse mucosa layer and Lamina mucosa conjunctiva tissue experimental group comparison with the control group, significant decrease was observed in mucosa layer the have (p ≤ 0.001)  and significant decrease was observed in the Lamina mucosa have(p ≤ 0. 01,  p ≤ 0.001). As a result, increasing the exposed time of mixing bleach and detergent, as time passed, increasing the tissue damage and changes.
Keywords
Bleach; detergents; chlorine; Mucosa layer; Lamina mucosa aerosol; Mice
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